Rohan Wickramasinghe¹, Udari Ruwanpathirana², K.H.P Madushani¹
1- National Hospital, Galle, Sri Lanka
2- German Sri Lanka Friendship Hospital for Women, Sri Lanka
Abstract Body
Introduction: This self-limiting illness runs a benign course and is a type of small vessel cutaneous vasculitis which usually present in age group of 04 to 24 months. Though aetiology is unknown usually present with a preceding infection, Vaccination or medication use. Present as Classical triad of fever, oedema and purpura predominantly over face and extremities. Incontrast to the dramatic eruptions the infants are systemically stable.
Case presentation: We report a one-month-old infant, previously thriving well, who presented with an acute onset of generalized non blanching purpuric lesions, “target-like” in appearance, predominantly over the trunk and face, without mucosal involvement or oedema. Extremities were spared. The infant was afebrile and clinically well despite the striking skin findings. Therewere no bleeding manifestations, systemic signs suggestive of infection, or hepatosplenomegaly and nor he was icteric. There was no history to suggest possible congenital infections. Dermatology opinion confirmed the diagnosis. Inflammatory markers were negative along with normal platelet counts ECG revealed no conduction blocks or arrythmia. Lesion diameter and colour intensity increased initially , but after two weeks had a self-limited resolution without any scarring or complications.
Conclusion: This rare and often under recognized disease presented in the subject infant in anunusual age of one month without oedema, fever or any associated prior illness. Given the early neonatal onset and prominent facial involvement in this well infant neonatal systemic lupus erythematosus (SLE) was considered in the differential diagnosis. Other differentials would be sepsis, congenital infections, thrombocytopenia and coagulopathy .