Introduction: Acute pancreatitis in paediatrics is a condition with diverse aetiologies and outcomes. Objectives: To identify clinical and biochemical factors associated with the severity and outcomes of children who were managed for an acute episode pancreatitis. Methods: Gastroenterology clinic in Lady Ridgeway Hospital manages 31 children with pancreatitis. A retrospective descriptive study with an analytical component was carried out using the clinic database records of 17 children diagnosed with an acute episode of pancreatitis. Children who had recurrent acute pancreatitis and chronic pancreatitis were excluded from this study . Results: The mean age was 7 .71 yeas (SD=±3.45). Majority was females (76.5%,13). Prevalences of mild, moderate, and severe episodes were 47 .1%, 29.4%, and 23.5% respectively . There was no statistically significant difference in sex (p=0.526) and mean age (p=0.826). There was no difference of duration of hospital stay among the groups (p=0.731). Prevalence of local complications were significantly higher in severe acute pancreatitis (p=0.037). Prevalences of local complications; acute peripancreatic fluid collection, acute necrotic collection, pseudocyst formation, and splenic vein thrombosis were 17 .6%, 11.7%, 11.7%, and 11.7% respectively . C-reactive protein (CRP) level was significantly higher in severe acute pancreatitis (p=0.032). There were no significant differences in other biochemical parameters. Underlying pancreatic disorders were found in 5.8% and hepatobiliary disorders in 29.4% respectively . Conclusions: Most of the acute pancreatitis’ episodes were mild in nature. Local complications were higher in severe pancreatitis. CRP level was significantly elevated in severe pancreatitis episodes. Limited number of cases in a single-center, remains as a limitation of this study .