Background : The prevalence of obesity in adolescents tends to increase worldwide. Obesity may increase the risk of metabolic disease, such as insulin resistance. An examination that can be used to determine insulin resistance is the measurement of homeostasis model assessment for insulin resistance (HOMA-IR). HOMA-IR calculations require fasting and invasive glucose and insulin measurements. Examination by taking blood in children using a needle, will cause pain and fear in the child. A simple examination, fast, not expensive and can be used widely is the measurement of anthropometry, such as waist circumference. This study determine the correlation between waist circumference and HOMA-IR in obese adolescent.
Material : This was an observational analytic study with cross-sectional study design. This research was conducted in Junior and Senior High School in Denpasar City. The target population in this study were obese adolescent in Denpasar City. The sample selection in this research used two stage random sampling method. This study was approved by the Research Ethics Committee of Medical Faculty in Udayana University, Sanglah Hospital, Denpasar.
Results : A total of 56 obese subjects aged 10 to 18 years were analyzed in this study. In this study, the prevalence of obesity in children aged 10-18 years is 3.3%. The prevalence of insulin resistance in this study was 16.3%. In correlation bivariate analysis it was found that waist circumference had a strong positive correlation with HOMA-IR with r = 0.646 and p = 0.000. Based on HOMA-IR and waist circumference regression equation, as every 1 cm increase in waist circumference will increase 18% HOMA-IR level.
Conclusions : This study found that strong positive correlation between waist circumference with HOMA-IR levels in obese adolescents. Increased waist circumference will increase the potential risk of obese adolescents to experience insulin resistance.