Abstract Ref Number = APCP396
CORRELATION BETWEEN VASOACTIVE INOTROPIC SCORE AND OUTCOME IN CHILDREN WITH SHOCK IN PEDIATRIC INTENSIVE CARE UNIT
Iin Fatimah,Khadijah Riski Sumitro,Dwi Putri Lestari,Neurinda Permata Kusumastuti,Arina Setyaningtyas,Ira Dharmawati,Abdul Latief Azis
Department of Child Health Faculty of Medicine Universitas Airlangga Dr Soetomo Hospital Surabaya Department of Child Health, Faculty of Medicine, Universitas Airlangga Dr Soetomo Hospital Surabaya, Indonesia
Background : Vasoactive and inotropic are the most common drug used in children with shock in Pediatric Intensive Care Unit (PICU). Vasoactive Inotropic Score (VIS) can be used to predict the outcome of children with shock. The aim of this study is to determine the correlation between VIS and outcome (ventilator used and mortality).
Material : This is a retrospective study. All children below 18 years with shock who were admitted to PICU during the periods of 1 November 2017 until 30 April 2018 with vasoactive and inotropic treatment were included. Demographic data, vasoactive inotropic drugs, and outcome were recorded from medical record. The calculation of VIS was described by Gaies, et al. Statistical analysis used mann whitney and regression test with p<0.05 being considered significant.
Results : There were 59 children who were treated with vasoactive inotropic drugs in this study. The median age was 36 (IQR 2-216) months, 52.5% were male, and 54.2% were using ventilator. The median VIS was 10 (IQR 3-25) and 52.5% were survive. Non survival patients had a higher VIS [median 12 (IQR 3-25)] than survival patients [median 5 (IQR 3-20)] (p<0.01), and higher ventilator used (35.6% vs 18.6%, p=0.005). Moderate correlation were found between VIS and mortality (r=0.463, p<0.01). Poor correlation were found between VIS and ventilator used (r=0.224, p=0.088).
Conclusions : There are a moderate correlation between VIS with mortality, and patients with higher VIS have higher mortality and ventilator used.
Keywords: children shock vasoactive inotropic score outcome