Abstract Ref Number = APCP229
ASSOCIATION BETWEEN CLINICAL SEVERITY AND THERAPEUTIC RESPONSE OF CHILDHOOD PNEUMONIA
Wigit Kristianto,Retno Asih Setyoningrum,Agoes Boediono
Djatiroto General Hospital Lumajang East Java Indonesia Department of Child Health, Faculty of Medicine,Airlangga University, Surabaya, Indonesia Nganjuk General Hospital, Nganjuk, East Java, Indonesia
Background : Early identification of children at risk of treatment failure could lower complication and mortality related to pneumonia. A numbers of clinical criteria has been developed to assess clinical severity of childhood pneumonia i.e. WHO classification, RISC, and PRESS. This study aimed to analyzed association between those criteria and the therapeutic response of pneumonia.
Material : Cross-sectional study was conducted on June-November 2017 at Nganjuk General Hospital, East Java involving 30 children aged 2-59 months with pneumonia. Clinical assessment was performed in the first contact of subjects with health provider. Therapeutic response was assess after 48 hours therapy. Association between variables were assessed using chi-squared test. P-value <.05 were considered to be statistically significant.
Results : The mean ages of subjects were 13.3 ± 12.2 years. The most common antibiotic used was cefotaxime (43.3%) and cefotaxime-gentamycin (40%). There were 23 (76,6%) subjects who had good response after 48 hours therapy. Worsen case was found higher in severe case of either WHO, RISC, or PRESS criteria (?(2)=2.283, p=.319; ?(2)=9.130, p=.010; ?(1)=15.134, p=.485; respectively).
Conclusions : This study suggests that severe case of pneumonia associated with higher risk for treatment failure. Our findings suggest that more concern is needed on severe pneumonia case management to reduce treatment failure.
Keywords: clinical severity therapeutic response pneumonia