Abstract Ref Number = APCP137
Simplified antiretroviral options for HIV-infected adolescence
Harapan Kita Women Children Hospital, Jakarta Indonesia
Adolescence is a critical transition period characterized by unique physical, biological, intellectual, behavioural and emotional growth and changes. For this reason, it is especially important that the adolescent stage of development and its potential impact on treatment adherence is distinguished from treatment support for adults and children. Adolescents are not children, nor are they adults.
Antiretroviral therapy is proven to prevent HIV-related morbidity, mortality, and transmission. The thoughtful selection of ART and the maintenance ofpatients on first-line treatment are therefore central to care for people living with HIV. A number of highly effective, well-tolerated, once daily dose,first-line ARV regimen options are available, includingnon-nucleoside reverse transcriptase (NNRTI), ritonavir(RTV)-boosted protease inhibitor (PI), and integraseinhibitor-based regimens. Fixed-dose combinations are preferred to aidwith ART adherence in adolescence. Patients taking once daily dose regimens have higherrates of adherence than those taking twice-daily dosed regimens.
Keywords: Adolescence, adherence, simplified antiretroviral