Abstract Ref Number = APCP1126
RISK FACTORS OF CEREBRAL PALSY IN SANGLAH HOSPITAL DENPASAR
Putu Diah Pratiwi,IGN Made Suwarba,Dewi Sutriani Mahalini
Department of Child Health
Background : Cerebral palsy (CP) continues to be one of the global burdens for both developed and developing countries. CP incidence in Indonesia is relatively high, estimated at 1 - 5 per 1,000 live births. CP lowers potential human resources and increases the burden of expenditure to facilitate the daily activities of the patients. Since the exact cause of CP is not known, identification of risk factors of CP is substantial to improve the quality of its comprehensive management, especially in Sanglah Hospital.
Material : This study was conducted at RSUP Sanglah Denpasar from January-June 2018, aimed to identify the characteristics and assess the risk factors of CP incidence with retrospective case-control design. Data obtained from registers, medical records and interviews. Bivariate analysis conducted using Chi-Square test, followed by multivariate analysis using multiple stepwise logistic regressions.
Results : This study involved 40 subjects for each control and case group. Advanced maternal age, advanced paternal age, maternal disease, history of pregnancy toxicity, poor obstetric history and inadequate antenatal care are pre-natal risk factors that are statistically significant for CP incidence. While gestational age <37 weeks, premature rupture of membranes, a history of prolonged labor and birth weight <2500 grams were significant perinatal risk factors for CP incidence. The final multivariate model from stepwise logistic regression demonstrated maternal disease (OR: 2.03, 95% CI: 0.49-8.43), inadequate antenatal care (OR: 3.05; 95% CI: 0.71 -20,44) and birth weight <2500 gram (OR: 9,85; 95% CI: 2,21-43,75) are the most significant risk factors for CP incidence, respectively.
Conclusions : A deeper understanding of risk factors will increase clinical awareness, develop and improve better services to reduce CP incidence rates.
Keywords: Risk Factor Cerebral Palsy Pediatric