Abstract Ref Number = APCP1083
CLINICAL PROFILE OF CHILDREN WITH CONGENITAL ANOMALIES OF THE KIDNEY AND URINARY TRACT IN RSUD DR SOETOMO SURABAYA
Chairunnisa Harahap,Ratih Dwi Andini,Risky Vitria Prasetyo,Ninik Asmaningsih Soemyarso,Mohammad Sjaifullah Noer
Department of Child Health Faculty of Medicine Universitas Airlangga Dr Soetomo Hospital Surabaya Indonesia
Background : Congenital Anomalies Kidney and Urinary Tract (CAKUT) are the leading cause of kidney failure in children and cause of 30-40% end-stage renal disease with obstructive uropathy as the main cause. CAKUT obstructive type are: vesico uretric junction obstruction (VUJO), pelvic uretric junction obstruction (PUJO), posterior uretral valve (UJO) and non-obstructive type are reflux, neurogenic and hypoplasia. The aim of this study is to describe the epidemiology of pediatric CAKUT at RSUD Dr. Soetomo Surabaya.
Material : Retrospective study from medical records of children with CAKUT at Dr. Hospital. Soetomo from April 2013 - April 2018. We focused on sex, age range, type of CAKUT and glomerulus filtration (GFR) rate value. Data processing using descriptive analysis with SPSS.
Results : A total of 94 Children on CAKUT abnormalities, 50.5% male. Median age 5.0 (SD 4.96, range 1-18) year. Median age onset of CAKUT 3.0 (SD 3.98, range 1-15) year. Symptom for obstructive type 50.5% and non-obstructive type 48.4%, most common CAKUT type in male were VUJO 18 (37.5%, p= 0.009) and in female neurogenic type 16 (34.8%, p = 0.031). Median basal glomerular filtration rate 102 (SD 56.28, range 2.7 - 266) ml/min/1.73 m2. Only 12 (12.6 %) patients need operative therapy.
Conclusions : CAKUT with dominant obstructive type is more common in male pediatric patient. Most of CAKUT can be handle with conservative therapy.
Keywords: Kidney Urinary Track Children CAKUT VUJO