Abstract Ref Number = APCP1048
RISK FACTORS OF REBOUND HYPERBILIRUBINEMIA IN POST PHOTOTHERAPY HYPERBILIRUBINEMIA INFANT IN INTERMEDIATE UNIT OF DR SOETOMO HOSPITAL
Alexander Josediputa,Mahendra Sampurna,Kartika Handayani,Dina Angelika,Martono Utomo,Risa Etika,Agus Harianto
Department of child health faculty of medicine Universitas Airlangga RSUD DR Seoetomo Surabaya Indonesia
Background : Post phototherapy rebound hyperbilirubinemia is a cause for readmission in some patient. However, this phenomenon data of rebound hyperbilirubinemia is lacking from Indonesia. The aim of our study is to describe the risk factor of post phototherapy rebound hyperbilirubinemia in infant.
Material : Cross sectional study of all infant with indirect hyperbilirubinemia who were treated phototherapy according to standard guidelines in neonate intermediate unit DR. Soetomo hospital for 6 months from June 2017 until December 2017. Bilirubin was measured 24 hours after phototherapy. Bilirubin rebound is considered as increasing total serum bilirubin that needs reinstitution of phototherapy.
Results : A total of 53 (44.9%) infants developed rebound hyperbilirubinemia. We revealed the following risk factor for rebound hyperbilirubinemia: 30 (56.6%) female infants, 37 (69%) low birthweight infants, 15 (28.3%) onset of jaundice on 4th day, 43 (81.1%, p 0.026) infants with oral gastric tube, 36 (67.9%, p 0.303) infants with history of caesarean section and 26 (49%) preterm infants.
Conclusions : Post phototherapy rebound hyperbilirubinemia should be considered in female, oral gastric tube, low birth weight, onset of jaundice on 4th day, history of caesarean section and preterm.
Keywords: Phototherapy Neonatal hyperbilirubinemia Rebound hyperbilirubinemia